Types Of Urinary Incontinence
There are several different types of incontinence that can develop from the symptoms of diabetes:
Urge Incontinence Having a sudden, intense urge to urinate followed by an involuntary loss of urine. You may also need to urinate frequently, even during the night.
Stress Incontinence Experiencing leakage when partaking in certain types of movement such as exercise, jumping, running, coughing, sneezing, laughing, etc.
Functional Incontinence Feeling an intense urge to urinate but failing to make it to the restroom in time due to conditions such as dementia, arthritis, or diabetic neuropathy.
Overflow Incontinence The frequent or constant dribbling of urine due to not being able to empty your bladder completely.
Mixed Incontinence You may experience more than one of the above types of incontinence.
Diabetes Warning Signs: 10 Early Symptoms You Shouldn`t Ignore
Here are 10 early symptoms that can help you recognize the onset of diabetes and aid you in getting your blood sugar under control before its too late.
1. You Pee a Lot
When the glucose level in your blood is high, your body tries to compensate by having your kidneys filter the excess sugar from your blood. The kidneys then flush the glucose from your body through your urine, increasing the frequency with which you must pee. You may also have an increase in urinary tract infections and notice that you get up more frequently at night to urinate.
2. Youre Always Thirsty
Because your kidneys are causing more frequent urination, it makes sense that your body is low on fluids, causing you to become dehydrated. And because youre dehydrated, you can feel thirsty all the time. You may also experience an extremely dry mouth.
3. Youre Hungry All the Time
When you have diabetes, your body doesnt properly use the energy in the foods you eat. Although glucose is present in the blood, your cells cant absorb it and begin to starve for energy. As a response, the cells communicate with the pancreas, saying they need more energy. The pancreas then increases the amount of insulin in the body, which tells the brain that youre hungry.
4. You Unexpectedly Lose Weight
5. Your Skin Becomes Very Dry
Another diabetes warning sign is dry, itchy skin. Caused by a combination of increased blood sugar levels and poor circulation, your skin may feel flaky and have an increased risk of infection.
Temporal Profile Of Ut Gene Expression In Dm
Genes examined for relative transcript expression levels compared with age-matched controls were grouped into the following four categories: glucose metabolism, cell survival and proliferation, cell-signaling receptors, and cell stress and cell death . Data are expressed as fold change in expression of each gene relative to age-matched control for each of the three temporal groups .
Temporal impact of DM on UT gene expression at: 3 wk 9 wk , and 20 wk . Genes were grouped into four categories: glucose metabolism cell survival and proliferation cell-signaling receptors cell stress and cell death . Values are expressed as fold change in gene expression relative to age-matched control values n = 45 ANOVA, *P< 0.05 or **P< 0.005. See text for abbreviations.
Temporal expression of the polyol pathway enzymes aldose reductase and sorbitol dehydrogenase , and, in addition, glucose transporter 1 were examined.
QPCR data indicated significant upregulation of AR at all three time points. SDH and GLUT1 were both significantly elevated at 3 wk and 20 wk DM, whereas 9 wk DM values did not significantly differ from those of age-matched control tissue .
Cell survival and proliferation.
Cell stress and cell death .
Relative to aged-matched control tissue all three time points, BNIP3 expression was significantly higher while COX2 expression was not .
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You Have Interstitial Cystitis
A few signs and symptoms include: pelvic pain that is alleviated by urination, a persistent need to urinate, and frequent urination, says Dr. Landry.
According to Dr. Nandi, Most people will urinate up to seven times a day, but those suffering with interstitial cystitis may urinate as much as 35 to 40 times a day, and many times the actual act of urination will only produce a few drops of urine and the distracting sense of urgency may not always subside after going. This symptom will occur all day and usually throughout the night, which can cause problems with sleep patterns. Plus, pain might be present, and itll intensify as the bladder fills up, he explains.
Unfortunately, the exact cause of interstitial cystitis is not known, but many factors probably play a role. For example, there might be a defect in the protective lining of the bladder as a result, a leak in the epithelium might allow toxic substances in urine to irritate the bladder wall. Additionally, there might be a genetic cause or an infectious etiology, Dr. Landry explains.
Regarding treatment, not every patient will respond, she cautions. But your doctor might recommend the following: oral medications, nerve stimulation techniques, bladder distension , medications instilled into the bladder, surgery, or acupuncture, which might also provide some relief, she says.
Recognising The Symptoms Of Polyuria
The most common sign of polyuria is producing abnormally large volumes of urine at regular intervals throughout the day and at night.
If you are concerned about the amount you urinate and think you may have polyuria, you should make a note each day of how much you drink how often you urinate and how much urine you produce every time you go to the toilet.
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You Might Have Benign Prostatic Hyperplasia
If youre having trouble getting a steady stream going, it could possibly be linked to an underlying prostate condition known as benign prostatic hyperplasia, or an enlarged prostate. At first, you might notice a decreased urine stream, where your urine just doesnt come out as forcefully, and that it just doesnt hit the wall like it used to, says Hollingsworth.
In fact, it also may take longer to empty a full bladder after some time with experiencing an over-full bladder, and it actually can injure the muscle of the bladder wall, leading to increasingly more bladder distention and damage, he says. When this condition reaches its more advanced stages, it can become difficult even to initiate urination, and this is bad news, as you have to pass urine more frequently as is, he says.
Luckily, alpha-blockers, antihistamines, and amitriptyline can help as potential treatments, he says. You can also try prostate artery embolization, a noninvasive procedure that can help shrink the enlarged prostate gland. But be warned: while its safe and effective, side effects can include blood in the urine, semen, or rectum, along with bladder pain, says Dr. Bortecen.
Temporal Changes In Barrier Morphology In Dm
When examined by TEM, the UT of bladders isolated from untreated/control animals was composed of umbrella, intermediate, and basal cell layers . A junctional complex was apparent between adjacent umbrella cells , and the apical cytoplasm was replete with discoidal or fusiform-shaped vesicles . DFV are responsible for delivery of uroplakins and other proteins to the apical surface of the cells . The apical plasma membrane of the umbrella cells was angular in appearance and composed of stereotypical hinge and adjacent plaque regions . SEM of the luminal surface of the umbrella cell layer in control tissue revealed a continuous layer of polyhedral-shaped cells . The apical surface of the umbrella cells appeared folded into parallel pleats , and the border between adjacent cells contained zippered apical membranes , which lie just above the tight junctions . The angular hinge regions and adjacent plaque regions were visible at higher magnifications .
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Youre Eating And Drinking Things That Irritate Your Bladder
Your bladder can get irritated, just like you when youre curled up in bed and realize, yup, you need to pee again. Coffee, alcohol, tea, carbonated beverages, spicy foods, citrus fruits, tomato-based products, and chocolate can all lead to bladder irritation, according to the Mayo Clinic, although this definitely doesnt happen to everyone who eats or drinks these things.
The thought is that these foods and drinks acidic, and that irritates the bladder wall, Dr. Matsunaga says. This does not happen to everyone. People with a condition like overactive bladder or interstitial cystitis may be more likely to be affected, Dr. Matsunaga says.
If You Ignore The Signs Of Diabetes
Its hard to ignore the signs of type 1 diabetes because symptoms can often appear quite quickly. But leaving it untreated can lead to serious health problems, including diabetic ketoacidosis, which can result in a potentially fatal coma.
Although the majority of people with type 1 diabetes are diagnosed in childhood and early adulthood, the symptoms are the same at any age. Adults with type 1 diabetes may not recognise their diabetes symptoms as quickly as children, which could mean their diagnosis and treatment may be delayed.
Type 2 diabetes can be easier to miss as it develops more slowly, especially in the early stages when it can be harder to spot the symptoms. But untreated diabetes affects many major organs, including your heart, blood vessels, nerves, eyes and kidneys. Being diagnosed early and managing your blood sugar levels can help prevent these complications. Use our Know Your Risk tool to check your risk of type 2 diabetes.
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How Do I Know If Its Frequent Urination
The characteristics of frequent urination are easy to spot. If you feel the need to pee more than four to eight times in one day, odds are that you have issues with frequent urination. Your healthcare provider may ask you a few questions to confirm this symptom. These could include questions like:
- What medicines are you taking?
- How much fluid do you usually drink?
- Are you drinking more than usual?
- Do you drink alcohol or caffeine?
During a visit, the healthcare provider may also take a urine sample to test for bacteria and white blood cells. UTIs are typically discovered this way. An ultrasound could be used to look for tumors or other structural issues that might be causing frequent urination. Another test you may have is a cystoscopy, which is used to look inside your bladder.
Foot Pain And Numbness Can Be Signs Of Diabetic Neuropathy
Over time, a prolonged exposure to high blood sugar level can damage the nerves throughout the body, called diabetic neuropathy. Some people may not have any symptoms of the damage, while others may notice numbness, tingling, or pain in the extremities.
Diabetic neuropathy usually starts in the feet and then it progresses upward, says Ovalle. Although most common in people who have had type 2 diabetes for 25 years or more, it can occur in people who have prediabetes as well. When it affects the nerves outside the brain and spinal cord, its termed peripheral neuropathy.
Numbness in the feet can increase their risk of infection: If you don’t feel a cut or scrape on your foot, you might not notice or properly treat it, he says.
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How To Know If Its Diabetes
Peeing a lot is a hallmark sign of both Type 1 and Type 2 diabetes, as the elimination of bodily fluids is sometimes your bodys only way of flushing excess blood sugar.
But urinating more than usual is just one of many signs and can be caused by any number of health conditions. If youre worried about diabetes, its important to look out for some of these other common diabetes symptoms:
- Fatigue. The cells inability to draw on glucose for energy can leave people with diabetes feeling depleted and exhausted much of the time. Dehydration only makes the fatigue worse.
- Weight loss. A combination of low insulin levels and an inability to absorb sugar from the blood can lead to rapid weight loss in people with diabetes.
- Blurred vision. A side effect of the dehydration caused by diabetes can be a severe drying of the eyes, which may affect vision.
- Swollen gums. Those with diabetes are at higher risk for infections, swelling, or buildup of pus in the gums.
- Tingling. A loss in sensation in the limbs, fingers, or toes is a common side effect of excess blood sugar.
If youre frequently urinating and worry it might be diabetes, keep an eye out for some of these other classic symptoms. If you notice several of them, or just want to be sure, consult a doctor.
What Is Frequent Urination
Inconvenient and disruptive to your daily life, frequent urination is when you need to urinate many times throughout a 24-hour period. This is a symptom of many different conditions and can have a wide variety of solutions. At some points in your life, like during pregnancy, you may need to pee more frequently. This can be a normal symptom of something like pregnancy and it usually passes after birth. However, frequent urination can be linked to other health issues that arent normal parts of life and dont fade over time. It can be a symptom of more serious conditions like diabetes, overactive bladder syndrome, UTIs or prostate problems. Needing to urinate frequently can even disturb your sleep. That full bladder that keeps waking you up in the middle of an otherwise good nights sleep is a condition called nocturia.
In many cases, your healthcare provider can help relieve this symptom by treating the underlying condition.
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Symptoms Develop Gradually With Type 2 Diabetes
The symptoms of type 2 diabetes develop graduallyso gradually, in fact, that its possible to miss them or to not connect them as related symptoms. Some people are actually surprised when they are because theyve gone to the doctor for something else .
If youre not insulin resistantand instead your body doesnt produce enough insulin to process glucose wellthe symptoms also develop gradually. Your body will be able to make do with lower insulin levels for awhile, but eventually, you will start to notice the following symptoms.
You Have Uterine Fibroids
Uterine fibroids, noncancerous growths that can grow in and on your uterus, are the most common benign tumors in women of childbearing age, per the U.S. Library of Medicine. Sometimes these tumors make their unwanted presence known by forcing you to pee all the time. This usually happens when a fibroid becomes large and presses on your bladder, according to the U.S. Department of Health and Human Services.
If youre experiencing symptoms you think are due to fibroids, try talking to your doctor. Theres a wealth of treatment options for the symptoms, from birth control to reduce pain and bleeding to a myomectomy to a hysterectomy and more.
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How Many Times A Day Is Normal To Urinate
Although going to the bathroom can be a nuisance, as you have to stop what youre doing and get up, its also an indicator of good or poor health. On an average day, you should pee six to seven times. Some people have to urinate even more frequently, such as up to 10 times over 24 hours. Others can urinate seldom, about four times a day.
If youre not urinating at least four times every day, then its worth scheduling an appointment with your primary care physician. An underlying health condition may be at play. Likewise, if you pee more than 10 times a day, you could have an overactive bladder or another condition causing it.
Besides just the frequency of your urination, symptoms that could accompany your condition include a strong odor when you urinate, painful urination, leaks if you dont go to the bathroom quickly enough, fever, having a hard time urinating, changes to urine color, bloody urine, and/or back pain.
Why Do Diabetics Pee A Lot At Night
But it can also happen at night. When theres too much sugar in your blood, which happens if you have diabetes, your kidneys have to work harder to get rid of it. This forces them to make more urine. The process doesnt stop just because youre snoozing.
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Kidney Infection Or Kidney Disease
Polyuria doesnt always indicate issues with the bladder. Sometimes, bacteria from the urinary tract migrate to the kidneys. Pyelonephritis, or kidney inflammation, is more common in puppies and senior dogs, but can occur at any time, and left untreated may lead to kidney failure. Excessive thirst and urination are signs to watch out for
What Does Undiagnosed Diabetes Feel Like
I remember feeling really tired and sleepy, but I didnt think anything of it as I was trying to juggle work and caring for my three children. When I got diagnosed, it made me think about my mum and her health. I thought she might have had diabetes too. She always used to feel tired and she had a boil on her leg that never seemed to heal. Read Saritas story in full.
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How Does My Body Produce Insulin
Insulin is produced by the pancreas, which is an organ that sits behind your stomach and intestines. Its a small gland thats actually part of the endocrine system where hormones are released into the bloodstream. This one, in particular, is responsible for producing insulin.
When levels of glucose rise above normal levels in the body, this triggers your pancreas to produce more insulin which attempts to lower blood sugar levels back down to normal. This allows cells to take glucose from the bloodstream and use it as energy.