Study Execution And Baseline Characteristics Of Participants
81 patients with T2D and ED were randomized to receive tadalafil or placebo for 6 months. Subsequently, 5 and 2 patients from tadalafil and placebo groups, respectively, discontinued treatment. In the tadalafil group, 3 patients were lost to follow-up, and two discontinued treatment. In the placebo group, one patient was lost to follow-up, and one patient was discontinued. Overall, 45 and 23 subjects in the tadalafil and placebo groups completed the trial . Baseline characteristics were well-matched between the groups at randomization and study completion .
Pathogenesis Of Ed In Diabetes
The pathogenesis of ED in diabetes is multifactorial, as it depends on both psychological and organic factors , as well as psychological and relationship issues, which often coexist. The proposed mechanisms of ED in diabetic patients are represented by vasculopathy, neuropathy, visceral adiposity, insulin resistance, and hypogonadism.
Diabetic vasculopathy concerns macroangiopathy, microangiopathy, and endothelial dysfunction. Macrovascular disease in diabetes corresponds to the atherosclerotic damage in the blood vessels, which limits blood flow to the penis. As mentioned, several cardiovascular risk factors associated with diabetes contribute to the genesis of penile arterial insufficiency: 23,35,36 all of them converge on endothelial dysfunction, which represents the common denominator leading to vascular ED.
Microvascular disease determines ischemic damage in the distal circulation and autonomic and peripheral neuropathy. Both somatic and autonomic neuropathies may contribute to diabetes-induced ED due to the impairment of sensory impulses from the penis to the reflexogenic erectile center,64 and reduced or absent parasympathetic activity necessary for relaxation of the smooth muscle of the corpus cavernosum.65
Erectile Dysfunction Treatment For Type 2 Diabetes
Erectile dysfunction is an extremely common issue. It impacts guys of any ages, from their 20s to elderly people. Nowadays, the issue can be treated with pills, shots or other drugs that are taken by mouth. But there are also some natural treatments you may want to try first for erectile dysfunction before considering medications. Erectile Dysfunction Treatment For Type 2 Diabetes
It is not uncommon to experience problems with erections sometimes. However, if it takes place consistently as well as interferes with a persons life, they can try various treatments.
Sometimes, Erectile Dysfunction has a physical cause, such as a treatable health and wellness condition or circulation trouble. Dealing with any type of hidden problems will certainly assist. Individuals can take steps to enhance their flow, such as doing regular workout, stopping smoking cigarettes , as well as making nutritional modifications.
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Why Do Men With Diabetes Have Erectile Dysfunction
The causes of erectile dysfunction in men with diabetes are complex and involve impairments in nerve, blood vessel, and muscle function.
To get an erection, men need healthy blood vessels, nerves, male hormones, and a desire to be sexually stimulated. Diabetes can damage the blood vessels and nerves that control erection. Therefore, even if you have normal amounts of male hormones and you have the desire to have sex, you still may not be able to achieve a firm erection.
Dont Ignore Erectile Dysfuntion: Its Treatable
If you are a man with diabetes, weve got good news and bad news about your sex life.
The bad news: Men with diabetes are three times more likely to report having problems with sex than non-diabetic men. The most common sexual problem is Erectile Dysfunction, or ED, sometimes called impotence. Even worse, because ED is such a private issue, many men feel embarrassed to discuss the problem with their doctor, or even their partner, so the problem is never addressed.
The good news: ED is one of the most treatable complications of diabetes. In fact, over 95 percent of cases can be successfully treated. With proven treatments available, diabetic men with ED have options. It isnt something youor your partnershould have to live with.
What ED Isand What It Isnt ED means the repeated inability to achieve or sustain an erection sufficient for sexual intercourse. Although sexual vigor generally declines with age, a man who is healthy, physically and emotionally, should be able to produce erections, and enjoy sexual intercourse, regardless of his age. ED is not an inevitable part of the aging process.
ED does not mean: An occasional failure to achieve an erection. The adage is true: It really does happen to everyone. All men experience occasional difficulties with erection, usually related to fatigue, illness, alcohol or drug use, or stress. It isnt fun, but it is totally normal.
You are not alone others have faced these difficulties. ED is treatable you do have options!
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What Sexual Problems Can Women With Diabetes Have
Low sexual desire and response, vaginal dryness, and painful sex can be caused by nerve damage, reduced blood flow to the genitals, and hormonal changes. Other conditions can cause these problems, too, including menopause. If you notice a change in your sex life, talk with your health care team. A physical exam, which will include a pelvic exam, and blood and urine tests may help your doctor find the cause of your problems.
What Bladder Problems Can Men And Women With Diabetes Have
Diabetes can cause nerve damage to your urinary tract, causing bladder problems. Overweight and obesity also can increase bladder problems, such as urinary incontinence . Managing diabetes is an important part of preventing problems that can lead to excess urination.
Your health care team may be able to help you manage your blood glucose levels and help you lose weight, if needed. Doctors use blood and urine tests to diagnose bladder problems or conditions with similar symptoms. Doctors also may use urodynamic testing to see what kind of bladder problem you have.
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What Are The Treatments
Treatment options include pills such as Viagra, injections, vacuum pumps, implantable pumps, supplemental testosterone, and psychological counseling. All of these treatments have pros and cons, so discuss your options thoroughly with your health care provider.
Remember that ED is a couples problem. Talk things over with your partner to be sure you both understand the problem youre having and agree on the treatment and goals you hope to achieve.
And dont forget that ED is one of the most treatable complications of diabetes. By working closely with your health care provider, you and your partner can find the solution that works best for you.
Permission is granted to reproduce this material for nonprofit educational purposes. Written permission is required for other uses. 2/01
Sometimes Ed Is A Red Flag For Other Health Conditions
Obesity, sleep apnea, and hypertension are just some of the underlying causes of erectile dysfunction and are in many cases precursors to a diagnosis of diabetes and/or heart disease.
Being obese or overweight not only increases your risk factor for diabetes, but it can also cause hypertension which damages blood vessels, making it difficult for them to carry blood throughout the vascular system, including to the penis.
Research suggests that sleep apnea may cause a dip in a mans testosterone and may also restrict oxygen, both of which are necessary for healthy erections.
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Work With Your Healthcare To First Pinpoint The Cause Of Your Ed
Erectile dysfunction is a very common issue, but rushing to your doctor for a prescription of Viagra isnt necessarily the answer. Work with your healthcare team to fully understand the cause of your ED before determining the best treatment plan for you!
And of course, work to improve your blood sugar levels, too.
How Can Diabetes Cause Or Worsen Ed
First, it helps to understand some diabetes basics. Diabetes mellitus is a condition in which the body cannot keep blood sugar at healthy levels. Thats usually because the body isnt making enough of the hormone insulin, which regulates blood sugar. Or it’s because your body isnt responding properly to the insulin it is making.
There are a few different types of diabetes, and type 2 is by far the most common, affecting 90% to 95% of patients, according to the CDC. Type 2 diabetes usually develops slowly over the course of many years. Chronically high levels of blood sugar can lead to serious health issues, including heart disease, nerve damage and kidney disease.
There are several ways that diabetes can affect erections:
- Nerve damage. When the nerves in the penis are damaged, it makes it less responsive to stimulation.
- Damage to blood vessels. Because diabetes can impair blood vessels, it may reduce blood flow to the penis. Since erections depend on healthy blood flow to the penile tissues, the result is less firm erections or none at all.
- Other health issues. Diabetes can also indirectly lead to obesity, sleep apnea and depression. All of these conditions can affect your general well-being and can worsen erectile dysfunction.
Get discreet care from the comfort of home and medication delivered to your door, starting at $1 per dose.
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Erectile Dysfunction: When Type 2 Diabetes Is Linked To Libido
Diabetes is a disease that can develop silently. Among its complications, erectile disorders can appear. our article reviews the erectile dysfunctions linked to diabetes and the means to prevent them.
Diabetes affects approximately 79 million people worldwide today. Among the complications, erectile dysfunction is too often overlooked, even though it really does affect the quality of life.
An erectile disorder is defined as an inability to obtain or maintain an erection sufficient to have a satisfactory sexual relationship. Erectile dysfunction is described as the inability to develop or maintain an adequate erection for a sexual connection to be satisfactory. It is called erectile dysfunction when it lasts for more than three months and when it occurs with each sexual encounter.
Why Diabetes Can Lead To Erectile Dysfunction
One of the lesser-known side effects of diabetes is an increased risk of erectile dysfunction. Experts think that circulatory problems from diabetes affect blood flow to the penis and make it difficult to get an erection. People with diabetes are three times more likely to have trouble maintaining an erection than people who don’t have diabetes.
Learn more about how to manage erectile dysfunction caused by diabetes.
Erectile dysfunction is a frustrating condition where your penis cannot get or maintain an erection firm enough for sex. It’s hard to admit that it’s a problem, but it’s more common than you might think. Nearly 30 million people in the United States have erectile dysfunction. Certain medications and some health conditions, including diabetes, significantly increase the risk of erectile dysfunction.
Erections are caused by an increase in blood flow to the penis. As the blood fills the erectile tissue, the tissue swells and gets larger and firmer. The swelling compresses the veins that let blood flow out of the penis, so your penis stays erect.
Diabetes can cause problems with blood flow in your extremities, including your penis. High blood sugar associated with diabetes may cause damage to blood vessels which affects blood circulation. If there is damage to the blood vessels in your genital area, you may have trouble becoming erect.
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Sexual & Reproductive Health In Women
In general, much less is known about sexual problems in women and this includes women with diabetes. The main sexual problems that women deal with are vaginal dryness, a decrease in sexual desire, pain during sex and trouble having an orgasm. Whether diabetes affects these problems is unclear although women who find it hard to come to terms with living with diabetes are more likely to report sexual problems.
Women with diabetes that is not well managed are more likely to have frequent bouts of thrush . In most cases, keeping blood glucose levels within the target range will help.
During periods or menopause, blood glucose levels may change. Women affected by this will need to adjust their treatment. Your doctor or Credentialled Diabetes Educator will help during these times.
Dont Hesitate To Address Your Health Challenges
Studies show the longer you have diabetes the better the chance youll experience some sort of sexual dysfunction.
The two conditions are interrelated and are serious and when not addressed, they can significantly decrease quality of life.
If youre experiencing symptoms of ED, its important to seek medical help from a doctor with expertise in this field.
The physicians at Norman Urology are dedicated to serving the urological needs of Norman and its surrounding communities. We treat our patients as partners as we discuss symptoms, diagnoses, and possible treatments.
Why not schedule an appointment with us today?
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Diabetes & Erectile Dysfunction: Did You Know Theres A Connection
At first consideration, it may not seem as though erectile dysfunction and diabetes are related.
However, each affect just about the same number of men in the U.S. around 18 million men and both are becoming increasingly more common.
Its easy to brush health warnings off, especially those related to conditions without symptoms, like early-stage diabetes. But what if I told you that getting your blood sugar under control could be the difference between having a healthy sex life and having trouble getting an erection at a very young age? asks Dr. Nathan Starke, a urologist specializing in mens health at Houston Methodist.
The reality is that diabetes and erectile dysfunction are intimately related. Poor blood sugar control can permanently ruin sexual function at a very early age, Dr. Starke adds.
In fact, a 2007 study found that 90% of men with erectile dysfunction either had diabetes or at least one of the risk factors for it, such as high blood pressure, high cholesterol and smoking.
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Population And Data Collection
Patients were enrolled by 114 diabetes outpatient clinics and 112 general practitioners. Physicians in all regions of Italy were identified and selected according to their willingness to participate in the project. All patients with type 2 diabetes were considered eligible for this project, irrespective of age, duration of diabetes, and treatment. In diabetes outpatient clinics, patients were sampled by using random lists, stratified by patient age . Each center was asked to recruit at least 30 patients, whereas general practitioners enrolled only those patients for whom they were primarily responsible for diabetes care. Patients were scheduled to be followed for 5 years, and information was to be collected at 6-month intervals. We report here a cross-sectional evaluation, based on baseline patient data.
General medical history and diabetes-specific data were collected by the patients physicians using forms specifically developed for the project by the scientific committee. For all clinical variables, the last value in the previous 12 months was requested. Because normal ranges for glycated hemoglobin varied among the different centers, the percentage change with respect to the upper normal value was estimated and multiplied by 6.0.
The questionnaire also investigated how often in the past 12 months the doctor in charge of diabetes care had asked the patient about problems with his sex life. Answers were given on a five-point scale ranging from at every visit to never.
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What Makes Me More Likely To Develop Sexual Or Bladder Problems
Youre more likely to develop sexual or bladder problems if you have diabetes and
- have high blood glucose that is not well controlled, also called high blood sugar
- have nerve damage, also called neuropathy
- have high blood pressure that is not treated
- have high cholesterol that is not treated
- are are overweight or have obesity
- are not physically active
Research also suggests that certain genes may make people more likely to develop diabetic neuropathy.2
The Lifestyle Changes That Reduce Your Diabetes Risk Can Also Help Prevent Erectile Dysfunction
The link between diabetes and erectile dysfunction has meaning for all men those who are already diagnosed with either diabetes or erectile dysfunction, as well as those who aren’t.
“Diabetes is underdiagnosed. It’s not uncommon for a man to find his way to my clinic for erectile dysfunction, only to be told shortly afterward that he has early, or even advanced, diabetes,” warns Dr. Starke. “If you’re having difficulty getting or maintaining an erection, it’s crucial to consult a men’s health specialist who considers your whole health, not just your penile health.”
And the sooner you get your diabetes under control, the better, since improving your blood sugar can help prevent the nerve and blood vessel damage that can contribute to devastating erectile dysfunction.
“In addition, the longer diabetes goes unchecked, the more damage it can cause to your body and the more irreversible its effects can become,” says Dr. Starke.
If you’ve already been diagnosed with type 2 diabetes, work with your doctor to ensure your condition is well-controlled, or at least well on its way to good control. He or she can also help you understand whether there are more steps you can take to better manage it.
Four lifestyle changes that can help get diabetes under control include:
And one last note, don’t get caught thinking you might be too young to worry about any of this.
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Pathogenesis Of Fsd In Diabetes
The normal female sexual response needs the integrity of the sensory and autonomic nervous systems in order to respond to erotic stimuli, as well as of the vascular districts that supply blood to the external genitalia and vagina. Both the smooth muscle relaxation of female genitalia erectile tissue and the enhancement of genital blood flow are dependent upon the action of nonadrenergic/noncholinergic neurotransmitters, such as vasoactive intestinal polypeptide and NO. The regulation of blood flow and clitoral erectile function is governed by the same NO/cGMP pathway in women as that involved in erectile function is in men. NO and PDE5 have been identified in human clitoral smooth muscle,115,116 indicating a key role of NO in female sexual function. Normal levels of various hormones are also required for physiologic sexual activity. Diabetes may affect all of these integrated systems, leading to sexual dysfunction. The mechanisms involved include hyperglycemia, infections, vascular and neurological damage, and hormonal disorders.117
Hyperglycemia reduces the hydration of the vaginal mucus membranes, producing poor vaginal lubrication and dyspareunia.118 Moreover, hyperglycemia increases the risk of genitourinary infections which, in turn, may lead to vaginal discomfort and dyspareunia.119