Monday, January 30, 2023

How To Use Insulin Glargine Injection

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Instructions For Use Semglee Injection Single

How to use SoloStar Pen for Injecting Lantus (Glargine) and Apidra (Glulisine) Insulin Music Version

Your healthcare professional has decided that SEMGLEE is right for you. Talk with your healthcare professional about proper injection technique before using SEMGLEE.

Read these instructions carefully before using your SEMGLEE. If you are not able to follow all the instructions completely on your own, use SEMGLEE only if you have help from a person who is able to follow the instructions.

People who are blind or have vision problems should not use SEMGLEE single-patient use prefilled pen without help from a person trained to use SEMGLEE single-patient-use prefilled pen.

Follow these instructions completely each time you use SEMGLEE to ensure that you get an accurate dose. If you do not follow these instructions you may get too much or too little insulin, which may affect your blood glucose.

SEMGLEE is a disposable pen for the injection of insulin. Each SEMGLEE contains in total 300 units of insulin. You can set doses from 1 to 80 units in steps of 1 unit. The pen plunger moves with each dose. The plunger will only move to the end of the cartridge when 300 units of insulin have been given.

If you have any questions about SEMGLEE, ask your healthcare professional, or call VIATRIS at 1-877-446-3679 .

  • Places to inject

  • Step1Check the insulin

  • Check the label on your SEMGLEE to make sure you have the correct insulin. SEMGLEE is blue with a purple injection button.
  • Take off the pen cap.
    • Step2Attach the needle

  • Wipe the rubber seal with alcohol.
    • Step3Perform a Safety test

    • Maintenance

    Carcinogenesis Mutagenesis Impairment Of Fertility

    In mice and rats, standard two-year carcinogenicity studies with insulin glargine were performed at doses up to 0.455 mg/kg, which was for the rat approximately 10 times and for the mouse approximately 5 times the recommended human subcutaneous starting dose of 10 Units/day , based on mg/m . The findings in female mice were not conclusive due to excessive mortality in all dose groups during the study. Histiocytomas were found at injection sites in male rats and male mice in acid vehicle containing groups. These tumors were not found in female animals, in saline control, or insulin comparator groups using a different vehicle. The relevance of these findings to humans is unknown.2

    Insulin glargine was not mutagenic in tests for detection of gene mutations in bacteria and mammalian cells and in tests for detection of chromosomal aberrations .

    In a combined fertility and prenatal and postnatal study in male and female rats at subcutaneous doses up to 0.36 mg/kg/day, which was approximately 7 times the recommended human subcutaneous starting dose of 10 Units/day , based on mg/m , maternal toxicity due to dose-dependent hypoglycemia, including some deaths, was observed. Consequently, a reduction of the rearing rate occurred in the high-dose group only. Similar effects were observed with NPH insulin.2

    Warnings For Other Groups

    For pregnant women: It is not known if insulin glargine is safe to use in pregnant women.

    Tell your doctor if youre pregnant or plan to become pregnant. You should only use insulin glargine during pregnancy if the potential benefit justifies the potential risk.

    For women who are breastfeeding: It isnt known if insulin glargine passes into breast milk. You and your doctor may need to decide if youll use insulin glargine or breastfeed. If you do both, your insulin glargine dosage may need to be adjusted, and your blood sugar level may be closely monitored.

    For seniors: People aged 65 years or older may be more sensitive to insulin glargine. This may raise your risk of a low blood sugar reaction. You doctor may start you on a lower dosage, and increase your dosage slowly.

    For children: Talk to your childs doctor about the use of insulin glargine in children. Special care may be needed.

    Read Also: Is Glaucoma Related To Diabetes

    Why Is This Medication Prescribed

    Insulin glargine products are used to treat type 1 diabetes . Insulin glargine products are also used to treat people with type 2 diabetes who need insulin to control their diabetes. In people with type 1 diabetes, insulin glargine products must be used with another type of insulin . In people with type 2 diabetes, insulin glargine products also may be used with another type of insulin or with oral medication for diabetes. Insulin glargine is a long-acting, manmade version of human insulin. Insulin glargine products work by replacing the insulin that is normally produced by the body and by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar.

    Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Using medication, making lifestyle changes , and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage , eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

    Lantus For Type 2 Diabetes

    Lantus Insulin glargine injection soloution used by diabetic patient ...

    Lantus is FDA-approved to improve blood sugar levels in adults with type 2 diabetes.

    Type 2 diabetes is a chronic condition where your cells dont respond to insulin as well as they should. Insulin is a hormone that enables sugar to pass from your blood into your cells. Because your cells dont react to insulin the right way, they cant get the energy they need to work properly. In addition, sugar levels build up in your blood. If not treated, this can lead to serious complications such as nerve damage.

    Some people with type 2 diabetes need to take insulin because their body stops making insulin on its own.

    Note: Lantus isnt approved to treat diabetic ketoacidosis , which is a possible complication of diabetes. For more information about DKA, see the Common questions about Lantus section below.

    Recommended Reading: Herbal Medicine For Diabetes In The Philippines

    Pharmacist Tips For Lantus

    Read the detailed “Instructions for Use” that comes with Lantus to ensure that you understand proper administration.

    For either vials or insulin pens, they can be kept at room temperature for 28 days.

    Inject at the same time each day, but rotate injection sites to prevent skin irritation or deformity.

    For proper use, inject Lantus under your skin in your upper arm, abdomen , or thigh .

    Never inject it into a vein or muscle. This can cause severely low blood sugar levels and infections.

    Do not dilute or mix with other types of insulin it will not work as intended and you may lose blood sugar control, which could be serious. However, your doctor may prescribe other short-acting insulins to use at different times of the day depending on your blood sugar control.

    Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.

    Do not re-use needles. Always use a new needle for each injection. Reusing needles increases your chance of having blocked needles, which can cause you to get the wrong dose of Lantus . Using a new needle for each injection also lowers your risk of getting an infection.

    When changing to Lantus from other basal insulins you may experience higher average fasting blood sugar levels in the first weeks of therapy. Monitor sugar levels daily to ensure that they are within a healthy range.

    Prices for Lantus start at just $341.25 with a GoodRx coupon. Theyâre fast, easy-to-use and free!

    How To Use The Lantus Solostar Insulin Pen

    Now that you and your doctor have decided Lantus is right for you, watch this step-by-step video to learn how to use the Lantus SoloStar pen. But always follow your healthcare providers instructions.

    Rotate your injection sites as instructed by your healthcare provider to reduce your risk of getting lipodystrophy and localized cutaneous amyloidosis . Do not use the same spot for each injection or inject where the skin is pitted, thickened, lumpy, tender, bruised, scaly, hard, scarred or damaged.

    • Removing and discarding the needle

    Super: WHAT WELL COVER:

    Step One: Inject the insulin

    Step Two: Attach the Needle

    Step Three: Perform a Safety Test

    Step Four: Select the Dose

    Step Five: Inject the Dose

    Step Six: Remove and Discard Needle

    It is important that you go over these instructions carefully before you using your SoloStar pen.

    Step one: check the insulin.

    SUPER: An unopened SoloSTAR® Pen should be refrigerated until first use. Do not store an opened SoloSTAR® pen in a refrigerator.

    Laura: If your SoloSTAR® pen is in cool storage, take it out 1 to 2 hours before you inject to allow it to warm up. Cold insulin may be painful to inject.

    SUPER: Check the label on your SoloSTAR® pen.

    Laura: First, check the label on your SoloSTAR® pen to make sure you have the correct pen and insulin. The Lantus® SoloSTAR® pen is gray with a purple injection button.

    Check the expiration date on the label of your pen. Do not use a SoloSTAR® pen after the expiration date.

    Storing your pen.

    Also Check: What Gauge Are Insulin Needles

    Important Safety Information For Lantus Solostar

    Lantus SoloSTAR is a disposable single-patient-use prefilled insulin pen. Please talk to your healthcare provider about proper injection technique and follow instructions in the Instruction Leaflet that accompanies the pen.

    for Full Prescribing Information for Lantus.

    for information on Sharps Medical Waste Disposal.

    to learn more about Sanofis commitment to fighting counterfeit drugs.

    *Eligibility Restrictions & Offer Terms:

    Insulins Valyou Savings Program: Sanofi insulins included in this program are: ADMELOG® 100 Units/mL, TOUJEO® 300 Units/mL, LANTUS® 100 Units/mL, and APIDRA® 100 units/mL.

    Sanofi Copay Program: This offer is not valid for prescriptions covered by or submitted for reimbursement under Medicare, Medicaid, VA, DOD, TRICARE, or similar federal or state programs including any state pharmaceutical assistance program. If you have an Affordable Care plan, you may still be qualified to receive and use this savings card. Please note: The Federal Employees Health Benefits Program is not a federal or state government healthcare program for purposes of the savings program. Void where prohibited by law.

    • LANTUS: Pay as low as $0 up to $99 for a 30-day supply, depending on insurance coverage. Maximum savings apply. Valid up to 10 packs per fill offer valid for 1 fill per month per 30-day supply

    for Full Prescribing Information for Lantus.

    Dosage: How Much Insulin Glargine Should I Take

    Glargine insulin injection | Lantus insulin injection | Lantus injection | Lantus insuiln

    Drug Content Provided and Reviewed by IBM Micromedex

    The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

    The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

    For injection dosage form :

    Basaglar® or Lantus®:

    For type 1 diabetes mellitus:

    • Adults and children 6 years of age and olderDose is based on your blood sugar and must be determined by your doctor.
    • Children younger than 6 years of ageUse and dose must be determined by your doctor.

    For type 2 diabetes mellitus:

    • AdultsDose is based on your blood sugar and must be determined by your doctor.
    • ChildrenUse and dose must be determined by your doctor.

    Toujeo®:

    For type 1 diabetes mellitus:

    • Adults and children 6 years of age and olderDose is based on your blood sugar and must be determined by your doctor.
    • Children younger than 6 years of age and olderUse and dose must be determined by your doctor.

    For type 2 diabetes mellitus:

    Read Also: Is Blindness From Diabetes Reversible

    Monitoring Your Blood Sugar Levels

    Did you know your blood sugar can be too low as well as too high? Those swings may happen with insulin treatment. Just know that monitoring your blood sugar as directed by your doctor gives you useful information that can help manage your diabetes.1

    CHANGES ARE NORMAL

    Things like stress, your diet, other medications, exercise, and more can affect your blood sugar. This is completely normal. Ask your healthcare provider how often you should test your blood sugar and what it should be. Thats a sure way to keep an eye on your levels and adjust as needed based on your doctors advice.

    STAY ALERT FOR LOW BLOOD SUGAR

    The most common side effect of insulins, including BASAGLAR, is low blood sugar , which may become serious and cause seizures or death. Its important to know the symptoms of low blood sugar, so if it does happen, youre ready to treat it immediately. Always remember that blood sugar below 70 milligrams per deciliter is too low.

    SELECT SAFETY INFORMATIONBasaglar may cause serious side effects that can lead to death such as:

    • Severe allergic reaction.
    • 4 ounces of juice or regular soda
    • 1 tablespoon of sugar, honey, or corn syrup
    • Hard candies, jellybeans, or gumdropssee food label for how many to consume

    Make a note about any episodes of low blood sugar and talk with your health care team about why it happened. They can suggest ways to avoid low blood sugar in the future.

    Talk to your doctor about low blood sugar and how to manage it.

    How To Choose An Injection Site

    Insulin should be injected into the fatty tissue just under your skin. Avoid injecting insulin into your muscle. Choose one of the following injection sites :

    • Your abdomen , except for the 2-inch area around your belly button. If youre injecting rapid-acting insulin, this is the best site to use.
    • The upper and outer part of your thighs. If youre injecting long-acting insulin, this is the best site to use.
    • The upper outer part of your buttocks .
    • The back part of your upper arms.
    • Only use this injection site if someone else is giving you the injection. If youre giving yourself the injection, its too hard for you to reach the correct area at the back of your arm.

    Figure 3. Injection sites

    Keep track of the injection site you use. Be sure to rotate the injection sites with each injection. Within each injection site, always inject 1 to 2 inches away from the last place you injected. This can help you avoid soreness and scar tissue.

    Make sure to inject at least 2 inches away from any incisions , scars, or stretch marks.

    Dont inject into an area thats tender, red, bruised, or hard.

    Also Check: How To Control Diabetes Without Insulin

    Dosage For Type 1 Diabetes

    If you have type 1 diabetes, the starting dose of Lantus is generally about one-third of your total daily insulin dose.

    Your total daily insulin dose is based on your weight. It typically ranges from 0.4 to 1.0 units per kilogram a day.

    For example, a 150-lb man weighs about 68 kg. If his doctor prescribes 0.5 units/kg a day, his total daily insulin dose would be 34 units a day. His starting dose of Lantus would be about one-third of 34 units, which is about 11 units of Lantus.

    Lantus is typically taken once a day, not twice a day.

    The drug is given as an injection just under your skin . You can inject Lantus in the skin of your upper arms, belly , or thighs.

    What Drugs And Food Should I Avoid While Taking Insulin Glargine

    got DIABETES? : Lantus SoloStar Insulin Glargine Injection (5 Pens ...

    Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

    Avoid medication errors by always checking the medicine label before injecting your insulin.

    Avoid drinking alcohol or using medicines that contain alcohol. It may interfere with your diabetes treatment.

    Recommended Reading: How Much Is A Insulin Pen

    What Medications Are Similar

    Lantus contains the ingredient insulin glargine. Insulin glargine is also available as other brand-name insulins:

    • Basaglar: Contains insulin glargine and is available in the same dosage of Lantus, which is 100 units per mL. Basaglar is indicated for use in adults with type 1 or type 2 diabetes and in children at least 6 years old with type 1 diabetes.
    • Semglee: A biosimilar product to Lantus. Semglee contains 100 units per mL insulin glargine, the same dosage as Lantus. Semglee is the first interchangeable biosimilar insulin product approved by the FDA. This means that Semglee can be substituted for the brand-name drug Lantus. Semglee is for use in adults with type 1 or type 2 diabetes and in children at least 6 years old with type 1 diabetes.
    • Toujeo: Also contains insulin glargine and is available in a higher dose than Lantus . It is used for adults with type 1 or type 2 diabetes.
    • Soliqua: A drug containing both insulin glargine and lixisenatide . It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

    Besides Lantus, other long-acting insulins include Levemir and Tresiba .

    Short-acting insulins are used in people with type 1 diabetes and sometimes used in people with type 2 diabetes. Examples include Humalog and Novolog .

    This list is a list of insulins also prescribed for diabetes. It is not a list of drugs recommended to take with Lantus. Ask your pharmacist or a healthcare practitioner if you have questions.

    What If I Miss A Dose

    If you miss a dose, take it as soon as you remember. If its almost time for your next dose, skip the missed dose and go back to your normal schedule.

    Dont take more than one dose in 24 hours unless your doctor tells you to. This could increase your risk for serious side effects, such as hypoglycemia .

    Medication reminders can help make sure that you dont miss a dose.

    Recommended Reading: Walmart 70 30 Insulin Pen

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