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How Does Diabetes Cause Kidney Failure

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Why Does Diabetes Cause Kidney Failure

How does diabetes cause kidney disease?

The kidneys perform an important function in cleaning the blood that flows through your body to all the cells in your organs and extremities. Since diabetes injures the small blood vessels in the kidneys, your kidneys are unable to do their job adequately. People with diabetes can end up retaining more water and salt than is healthy, which can result in weight gain and swelling.

Additionally, diabetics often experience nerve damage, which can cause difficulty emptying their bladder. When this occurs, the pressure from a full bladder can hurt the kidneys. You can also develop a bacterial infection, which occurs in urine with a high sugar level. These results can damage the kidneys and impair their functioning.

One of the key indicators pointing to diabetic kidney disease is the presence of albumin in the urine. If you have diabetes or if diabetes runs in your family, its important to have your doctor test your urine for albumin on an annual basis. Even if you have no other symptoms of kidney disease, albumin excreted in the urine can exist long before the evidence points to kidney disease. According to the MSDH, 10 to 40 percent of those with Type 2 diabetes eventually will suffer from kidney failure. Fortunately, not everyone with diabetes develops kidney diseasea lot depends on genetics, blood glucose control, and blood pressure.

How Can I Tell If I Have Diabetic Kidney Disease

Most people with diabetic kidney disease do not have symptoms. The only way to know if you have diabetic kidney disease is to get your kidneys checked.

Health care professionals use blood and urine tests to check for diabetic kidney disease. Your health care professional will check your urine for albumin and will also do a blood test to see how well your kidneys are filtering your blood.

You should get tested every year for kidney disease if you

Risk Factors And Pathogenesis

Diabetic nephropathy develops in, at most, 40% of patients with diabetes, even when high glucose levels are maintained for long periods of time. This observation raised the concept that a subset of patients have an increased susceptibility to diabetic nephropathy. Furthermore, epidemiological and familial studies have demonstrated that genetic susceptibility contributes to the development of diabetic nephropathy in patients with both type 1 and type 2 diabetes. The main potentially modifiable diabetic nephropathy initiation and progression factors in susceptible individuals are sustained hyperglycemia and hypertension . Other putative risk factors are glomerular hyperfiltration , smoking , dyslipidemia , proteinuria levels , and dietary factors, such as the amount and source of protein and fat in the diet.

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Is It Possible To Tell If I Have Diabetic Kidney Disease

Most humans with diabetic kidney ailment mostly no longer have symptoms. The handiest manner to recognize when you have a diabetic kidney ailment is to get your kidneys checked.

Health care experts use blood and urine assessments to test for a diabetic kidney ailment. Your fitness care expert will take a look at your urine for albumin and also will do a blood take a look at to peer how nicely your kidneys are filtering your blood.

You must get examined every 12 months for kidney issues in case you:

  • have diabetes type 2
  • have had diabetes type 1 for over a period of five years

What Is Chronic Kidney Disease

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Your kidneys are important because they keep the rest of your body in balance. They:

  • Remove waste products from the body
  • Balance the bodys fluids
  • Help keep blood pressure under control
  • Keep bones healthy
  • Help make red blood cells.

When you have kidney disease, it means that the kidneys have been damaged. Kidneys can get damaged from a disease like diabetes. Once your kidneys are damaged, they cannot filter your blood nor do other jobs as well as they should.

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How Does Diabetes Lead To Kidney Disease

People with diabetes who have consistently high blood sugar and high blood pressure levels have an increased risk of developing kidney disease. This is because high blood sugar and high blood pressure levels can cause the nephrons in the kidneys to become damaged, and therefore they cannot filter blood and waste products properly.

As some nephrons become damaged, the remaining nephrons have to work harder this increases pressure in these nephrons, which in turn causes them to succumb faster to damage. It becomes a vicious cycle: as more nephrons become destroyed by high glucose and high blood pressure, the pressure within the kidneys, as well as blood pressure, both increase. This causes even more harm to the kidneys.

As the damage and pressure within the kidney increases, two things occur:

  • The blood vessels within the nephrons become leaky and protein from the blood falls through the nephrons into the urine. As kidney disease progresses, larger amounts of protein spill into the urine this is called proteinuria, and it is measured by a urine test. This test can determine early stages of kidney disease before there are signs or symptoms.
  • The flow through the kidney starts to decrease. This causes a build-up of waste products in the blood. Again, this may not cause any signs or symptoms until it is at a critical level. However, the flow through the kidney can be followed by a blood test early on to watch for any progression of kidney disease.
  • What About A Kidney Transplant

    Dialysis saves lives for those with chronic kidney failure, but it serves to provide only about ten percent of a normally functioning kidneys ability to filter wastes from the body. In addition, dialysis can cause other serious health issues including:

    • anemia or decreased number of normal red blood cells
    • nerve damage
    • high blood pressure

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    What Happens To The Kidneys In Diabetes

    The main function of the kidneys is to filter waste products and excess water from the bloodstream so that they can be excreted in the form of urine. This is carried out by a system of tubes and blood vessels known as nephrons. Inside the nephrons are tiny blood vessels called capillaries and tiny urine-collecting tubes. One of the major structures in the nephron is a group of blood vessels known as the glomerulus, which acts as a filter.

    Having high blood glucose levels can interfere with the function of the glomerulus. The filtering function of the kidneys doesnt work properly and proteins start to leak from the blood into the urine.

    High blood glucose levels can also cause scarring of the glomerulus . As the scarring gets worse, the kidneys stop being able to filter waste products from the blood.

    When enough glomeruli have been damaged, kidney failure results.

    People who have diabetic nephropathy also often have high blood pressure. High blood pressure can further contribute to kidney damage.

    What Is The Future Outlook For Patients With Diabetes

    Diabetes Symptoms & Treatments : Why Does Diabetes Cause Kidney Failure?

    Today, more and more research dollars are spent on diabetes research. Hopefully, the prevention and cure of diabetes is in our future. In the meantime, you can manage your diabetes better with:

    • home monitoring of your blood glucose levels
    • maintaining an awareness of controlling your blood pressure, and possibly monitoring your pressure at home
    • following your special diet.

    If you would like more information, please contact us.

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    How To Keep My Kidneys Healthy If I Have Diabetes

    Always keep controlling diabetes, blood sugar level by which our kidney functions appropriately, and urinate daily. Remember, there are two types of diabetic diseases: Type1 and Type2 diabetes. Control over the types of diabetes keeps your kidneys protected from diabetes cause kidney disease.

    to find more information related to health.

    Where Can I Get More Information

    The National Kidney Foundation has free booklets that provide more information about diabetes and kidney disease. Call the national toll-free number 855.653.2273 and ask for free booklets. You can see these and other titles at

    If you would like more information, please contact us.

    Save this content:

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    Are You A Diabetic Here’s What High Blood Sugar Levels Can Do To Your Kidney Heart And Brain

    Written by Editorial Team | Updated : June 13, 2015 3:11 PM IST

    Diabetes is a complex, progressive disease that can lead to long-term complications if the sugar levels are not kept under control. As a diabetic, you may be aware about medicines, devices and remedies that can help you to control your sugar levels. But along with that you also need to understand what complications you may have to face if you fail to adhere to your medications and keep your blood sugar in check.

    Dr Mitali Joshi, consultant at LifeSpan, highlights one such manifestation of type 2 diabetes called the Hyperosmolar Hyperglycemic Nonketotic Syndrome , a condition that can result in kidney failure, stroke and diabetic coma.

    What is HHNS? How does it affect a diabetic? Is it an emergent condition?

    Diabetic Kidney Disease Stages

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    Early treatment could help slow down kidney disease progression in kidney patients if they were getting more numerous renal problems. There are five stages of kidney disease. Look at the below image.

    Sometimes our glomerular filtration rate is used to get the exact idea about our kidney disease stage. Identifying the scene is essential because it will affect your treatment plans. To calculate your GFR, the doctor will use the results from a creatinine blood test along with our age, gender, and body physique.

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    What Causes Kidney Disease

    One of the main jobs of your kidneys is to filter your blood. They get rid of extra fluid and waste products from your body through your urine.

    High blood glucose levels can damage the small blood vessels and tiny filters in your kidneys. High blood pressure can also do this too. This can cause them to leak and not work as well. When this happens, abnormal amounts of protein from the blood can leave your body in your urine. This is often an early sign of kidney disease.

    How Can I Prevent It

    Diabetic kidney disease can be prevented by keeping blood glucose in your target range. Research has shown that tight blood glucose control reduces the risk of microalbuminuria by one third. In people who already had microalbuminuria, the risk of progressing to macroalbuminuria was cut in half. Other studies have suggested that tight control can reverse microalbuminuria.

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    How Does Diabetes Affect My Kidneys

    Diabetes causes injury to small blood vessels throughout the body. Small blood vessels in the kidney are often involved. This causes protein to spill into the urine. One type of protein, albumin, is detected in the urine even during early, mild kidney disease. If progressive chronic disease develops in kidney blood vessels, the kidneys cannot function normally and kidney failure develops.

    If You Are A Living Kidney Donor Or Plan To Donate Your Kidney In The Future

    Diabetes Affect Kidneys!! How to prevent of KIDNEY FAILURE?

    The COVID-19 vaccine clinical trials did not get information about the effect on people who have donated their kidney in the past. However, if you are in good health and do not have a history of severe side effects from vaccines, there are no special safety concerns for you at this time. Talk to your doctor if you have questions about the COVID-19 vaccine and being an organ donor.

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    How Does Diabetes Cause Kidney Disease

    High blood glucose, also called blood sugar, can damage the blood vessels in your kidneys. When the blood vessels are damaged, they dont work as well. Many people with diabetes also develop high blood pressure, which can also damage your kidneys. Learn more about high blood pressure and kidney disease.

    Diabetes Is The Leading Cause Of Chronic Kidney Disease

    According to the Centers for Disease Control, over 17 million Americans have diabetes. Unfortunately, one-third does not realize they have the disease. Diabetes is the number one cause of chronic kidney disease . In 1999, almost 44% of patients who needed dialysis had diabetes as the underlying cause for their kidney disease. The numbers continue to rise today.

    How diabetes damages the kidneys

    Diabetes is a disease that affects the bodys ability to produce or use insulin. When the body turns the food eaten into energy , insulin is used to move this sugar into the cells. If someone produces little or no insulin, or if the body cannot use the insulin , the sugar remains in the bloodstream instead of going into the cells. Over time, high levels of sugar in the blood damage tiny blood vessels throughout the body including the filters of the kidneys. As more damage occurs to the kidneys, more fluid and waste remain in the bloodstream instead of being removed.

    Symptoms of diabetes

    The American Diabetes Association lists the symptoms of diabetes as:

    • Frequent urination
    • Blurry vision

    Lack of an early diagnosis compounds the problem

    Type 1 diabetes is typically diagnosed early because its symptoms are severe and rapid. A treatment plan can then be put in place and continued. Unfortunately, Type 2 diabetes often goes undiagnosed for many years because early symptoms are not severe.

    Obesity is on the rise

    High blood pressure can accompany Type 2 diabetes

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    Questions To Ask Your Doctor

    • I have diabetic nephropathy. Could my kidneys fail?
    • Will I need dialysis for my kidneys?
    • Are there any medicines that I shouldnt take?
    • Could herbal supplements be dangerous for me?
    • What is the best thing I can to prevent further damage to my kidneys?
    • Are there any medicines that I can take to help prevent damage to my kidneys?

    How Much Is A Kidney Transplant In The India

    10 Free Tips: How Does Diabetes Cause Kidney Disease ...

    Answer Wiki The Cost of kidney transplant in India lies between Rs. 3,00,000 to Rs. 7,50,000 This price is highly competitive when compared to other countries where you have to pay a lot more for the same quality treatment you get here. Kidney Transplant in India can be done in many cities. Even though people prefer particular city as their destination so that they can know exactly kidney transplant cost in India, within the cities and can compare to their own country. Now you will come to know the detail cost of kidney transplant surgery city wise in India. let us understand the cost of kidney transplant in Major advanced Indian cities like New Delhi, Mumbai, Bangalore, Hyderabad, Chennai 1.Kidney transplant cost in New-Delhi- Minimum =3,50,000 INR to Maximum=9,00,000 INR 2. Kidney transplant cost in Mumbai – Minimum =4,00,000 INR to Maximum=10,00,000 INR 3. Kidney transplant cost in Bangalore – Minimum =4,30,000 INR to Maximum=9,00,000 INR 4. Kidney transplant cost in Hyderabad – Minimum =3,50,000 INR to Maximum=8,90,000 INR 5.Kidney transplant cost in Chennai – Minimum =3,50,000 INR to Maximum=8,50,000 INR Continue reading > >

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    Does Albuminuria As A Result Of Diabetic Nephropathy Automatically Imply Chronic Kidney Disease

    In people having long term badly managed diabetes , protein loss repeatedly found in the urine is a sign of diabetic nephropathy, so indeed chronic kidney disease, which is the most frequently diagnosed underlying cause of end stage renal disease needing chronic dialysis and/or renal transplantation. From Trends in Chronic Kidney Disease This can be ameliorated by angiotensin converting enzyme inhibitors or angiotensin receptor blockers even if the blood pressure isn’t elevated. An isolated case of albuminuria is not a diagnosis, but it needs to be investigated further. Where I live, usually a second urine test is done a few weeks later, followed by a 24-hour urine protein test. I’m not certain what the diabetes guidelines for the US say, but they shouldn’t be much different. Badly managed glucose levels cause kidney damage, which leads to the proteins leaking into the urine. If the kidneys are working properly, there are no proteins in urine, no matter how high your glucose levels might be. Persistent albuminuria with no other cause is enough to diagnose chronic kidney disease in a diabetic patient.Continue reading > >

    Serum Creatinine Blood Test

    A serum creatinine blood test measures creatinine levels in your blood. Your kidneys remove creatinine from your body by sending creatinine to the bladder, where it is released with urine. If your kidneys are damaged, they cannot remove the creatinine properly from your blood.

    High creatinine levels in your blood may mean that your kidneys are not functioning correctly. Your doctor will use your creatinine level to estimate your glomerular filtration rate , which helps to determine how well your kidneys are working.

    What Increases My Chances Of Developing Diabetic Kidney Disease

    Having diabetes for a longer time increases the chances that you will have kidney damage. If you have diabetes, you are more likely to develop kidney disease if your

    • blood glucose is too high
    • blood pressure is too high

    African Americans, American Indians, and Hispanics/Latinos develop diabetes, kidney disease, and kidney failure at a higher rate than Caucasians.

    You are also more likely to develop kidney disease if you have diabetes and

    • smoke
    • have heart disease
    • have a family history of kidney failure

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